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Carisoprodol is available as a 250-mg or 350-mg tablet and in combination with aspirin (soma compound) and with aspirin and codeine (soma compound with codeine). Carisoprodol dosing should not exceed four doses in a 24-hour period (Table 41.2). Similar to other muscle relaxants, carisoprodol has additive sedative.
4, 10–13 Read full chapter. The plasma half-life is 8 hours and the duration of action is 4 to 6 hours. The drug is supplied as 350-mg tablets and the recommended dose is one tablet taken four times daily. The onset of action of carisoprodol is 30 minutes. Carisoprodol is also available in combination with aspirin (Soma Compound) or aspirin and codeine (Soma Compound with Codeine).
Andrew Dubin, in Practical Management of Pain (Fifth Edition), 2014.
A report had appeared demonstrating the abuse potential, ultimay contributing to a rise in concern about its effects.
(2015) Assessment of subunit-dependent direct gating and allosteric modulatory effects of Carisoprodol at GABAa receptors.
Adenosine reuptake inhibition appears to exist, which may contribute to the sedative action.
Other depressants, including ethanol, opioids, and benzodiazepines.
It is rapidly absorbed from the GI tract and distributed in the CNS.
Some countries have responded by moving away from the substance.
Carisoprodol should be used with caution in patients with CNS depression. Carisoprodol is a centrally acting agent and can exacerbate CNS depression. Carisoprodol may impair mental or physical abilities required for driving or operating machinery; carisoprodol-associated motor vehicle accidents have occurred in.
Carisoprodol is not recommended for neonates, infants, children, or adolescents under the age of 16 years because safe and effective use has not been established in pediatric patients. No pediatric specific problems have been documented.
drowsiness / Early / 13.0-17.0 xerostomia / Early / 0-10.0 dizziness / Early / 7.0-8.0 headache / Early / 3.0-5.0 nausea / Early / 4.0-4.0 insomnia / Early / 1.5-1.5 vertigo / Early / Incidence not known syncope / Early / Incidence not known weakness / Early / Incidence not known tremor / Early / Incidence not known irritability / Delayed / Incidence not known agitation / Early / Incidence not known mydriasis / Early / Incidence not known lethargy / Early / Incidence not known diplopia / Early / Incidence not known asthenia / Delayed / Incidence not known rash (unspecified) / Early / Incidence not known fever / Early / Incidence not known pruritus / Rapid / Incidence not known urticaria / Rapid / Incidence not known flushing / Rapid / Incidence not known dyspepsia / Early / Incidence not known vomiting / Early / Incidence not known.
Carisoprodol is a prescription medication used to relax muscles and relieve pain due to muscle spasms. Carisoprodol belongs to a class of drugs called muscle relaxants, which help prevent muscle spasms without affecting overall muscle control. This medication comes in tablet form and is taken 3 times a.
Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. The FDA categorizes medications based on safety for use during pregnancy.
Your doctor may adjust your dose of carisoprodol if you are a poor metabolizer.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See “Drug Precautions” section. Serious side effects have been reported with carisoprodol.
l your doctor if you are pregnant or plan to become pregnant.
However, if overdose is suspected, seek emergency medical attention.
Carisoprodol is used to relax certain muscles in your body and relieve the discomfort caused by acute (short-term), painful muscle or bone conditions. However, this medicine does not take the place of rest, exercise, physical therapy, or other treatments that your doctor may recommend for your medical condition.
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It acts on the central nervous system (CNS) to relax muscles. Carisoprodol is a skeletal muscle relaxant.
Portions of this document last updated: March 01, 2017.
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This medicine is available only with your doctor's prescription.
However, this medicine does not take the place of rest, exercise, physical therapy, or other treatments that your doctor may recommend for your medical condition. Carisoprodol is used to relax certain muscles in your body and relieve the discomfort caused by acute (short-term), painful muscle or bone conditions.
This product is available in the following dosage forms: